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German defense minister visits India, focusing on $5.2 billion submarine project, hoping to strengthen military cooperation.

　　[Cheng Shijian, special correspondent of Global Times in Pakistan] According to a report by Indian TV station in New Delhi, German Defense Minister Pistori Uss visited India on the 6th and held bilateral talks with Indian Defense Minister Rajnath Singh, seeking to strengthen military cooperation between the two countries. This is the first time that a German Defense Minister has visited India since 2015.

　　Pistori Uss said at a press conference that European countries lack the "will and channels" to provide weapons to India, and that India’s current arms imports are "too dependent on Russia, which is not in India’s national interest". He said that German naval ship supplier TKMS may participate in India’s bidding for the purchase of six submarines at a cost of US$ 5.2 billion. In addition, Germany also hopes to strengthen military cooperation with Indian navy and air force.

　　According to Deccan Herald reported on the 7th, Pistori Uss went to Mumbai to visit the Indian Western Naval Command and India Mazagan Dock Co., Ltd., and attended the meeting between Mazagan Dock Co., Ltd. and TKMS. German newspaper frankfurter allgemeine zeitung reported that the two companies may sign a memorandum of understanding on submarine project cooperation.

　　According to DPA, Pistori Uss called India "one of Germany’s most important partners in the region", and the German government sent a frigate to the Indo-Pacific region in 2021, and will deploy maritime forces in the region again in 2024, including a frigate and a supply ship. Singh said that with India’s rich and skilled labor force and Germany’s advantages in science and technology and investment, India and Germany can establish a "symbiotic relationship" in the defense field on the basis of common goals and complementary strengths. Singh also said that he plans to invite German companies to invest in the "defense industrial corridors" in Uttar Pradesh and Tamil Nadu, and to incorporate Indian defense industry into the German military industrial system to increase the flexibility of the supply chain.

　　India’s Firewire magazine said that Pistori Uss’ visit to India was ostensibly to persuade India to reduce its dependence on Russian armaments, but the actual purpose was that Germany hoped to win over some Indian markets in the field of defense.

　　According to The Hindu, the day before meeting with Pistori Uss, Singh met with US Defense Secretary Austin in New Delhi on the 5th, which was Austin’s second visit to India since he took office as Defense Minister. The report said that the two sides discussed ways to further expand bilateral strategic contacts before Indian Prime Minister Modi visited Washington, and discussed some new defense industry cooperation projects.

　　The Associated Press said that Austin’s visit coincided with India’s efforts to strengthen its defense industry by acquiring new technologies and reducing its dependence on imports, especially Russian imports. Although the conflict between Russia and Ukraine continues, Russia is still India’s largest supplier of military equipment.

The latest progress in AIDS treatment is expected to rewrite the future treatment pattern.

Original Lingjun medical field

The study once again suggests that monoclonal antibody combined therapy is one of the most promising methods to completely cure AIDS.

Author | Ling Jun

Source | "Medical" WeChat official account

On June 1, 2022, the top magazine Nature published a heavy research on AIDS treatment.

In the experiment, as an alternative therapy to conventional antiretroviral therapy (ART), the HIV level in the infected person was controlled for up to 43 weeks after the combination of two broad-spectrum neutralizing monoclonal antibodies.

Researchers believe that in the future, HIV-infected people may not need ART treatment every day, but only need low-frequency (such as biennial) medication, and perhaps combined with long-acting antiretroviral drugs, they can return to normal life.

Based on this research, Professor Lu Hongzhou, Dean of the Third People’s Hospital of Shenzhen, told the "medical field" that monoclonal antibody combination therapy is one of the most promising methods to completely cure AIDS. "At present, many studies have shown that low-frequency use of monoclonal antibody combination therapy can effectively maintain virus inhibition, but the virus will rebound after stopping drug use. It is expected to change this situation by further screening and developing long-acting monoclonal antibodies."

High level of HIV inhibition

Up to 43 weeks

Today, 40 years later, AIDS is no longer a "terminal disease".

With the advent of "highly effective antiretroviral therapy" (HAART), that is, cocktail therapy, the virus level in HIV-infected people has been effectively controlled, even reaching "non-infectious" in clinical indicators, and the life expectancy is close to that of ordinary people.

But the defects are also obvious. HIV-infected people need to take medicine every day and for life, and their compliance varies from person to person. Once the drug is stopped, the virus level in the body will rebound quickly. In addition, lifelong use of drugs may have long-term side effects and create the possibility for the emergence of drug-resistant viruses.

This time, the researchers conducted a small phase I clinical trial, and tested the combination therapy of two monoclonal antibodies, 3BNC117 and 10-1074, which are aimed at different targets, and are expected to bring a breakthrough in "long-term treatment".

The trial is divided into two parts. The first is a randomized, double-blind, placebo-controlled study involving 14 infected people. They first received antiretroviral therapy (ART), then stopped taking drugs and received up to eight times of "monoclonal antibody combination therapy" or placebo-twice in the first month and once a month thereafter.

The results showed that, except one infected person who secretly recovered ART for fear of illness, the HIV levels of the other six placebo subjects all rebounded 28 weeks ago, and ART treatment must be restarted immediately, with a median time of 9.4 weeks.

All 7 people in the monoclonal antibody combined treatment group did not need to restart ART. Five of them showed a very high level of HIV viremia inhibition, and the effect lasted for up to 43 weeks, that is, 19 weeks after stopping the "monoclonal antibody combination therapy".

However, it is worth noting that in the second part of the experiment, the researchers recruited another five HIV-infected people who had not received ART. After the start of "monoclonal antibody combined therapy", only two people achieved complete inhibition of HIV, and the average duration was 41.7 weeks.

Further research found that the other three infected people whose virus levels were not controlled were resistant to two kinds of monoclonal antibodies.

The same findings also appeared in the first trial. Although there was no need to restart ART treatment in the treatment group, two people had a partial rebound in virus level in the first 8 weeks, which was also due to the existence of drug-resistant viruses in the body.

The researchers pointed out, "This suggests that the premise of treatment is that there can be no virus resistant to the corresponding monoclonal antibody in the infected person before administration.

Can we finally realize the "clinical cure" of AIDS?

This is not the first time to study the treatment of AIDS with 3BNC117 and 10-1074.

As early as 2018, the team of Professor Nussenzweig from Rockefeller University published a paper in Nature: After stopping ART, using this monoclonal antibody combination can effectively inhibit HIV for 15-30 weeks (median 21 weeks).

"They can inhibit HIV in infected people for several months, and may produce new methods to prevent and treat AIDS." In 2020, Rockefeller University published a document in official website, and the antibody combination has been acquired by a large multinational pharmaceutical company in the United States.

On April 13th, 2022, Professor Nussenzweig and his team updated the research progress again. All the infected people who received the combination therapy of the monoclonal antibody for 7 times still maintained virus inhibition within 21 to 48 weeks after stopping the injection.

Professor Lu Hongzhou told the medical community that monoclonal antibody therapy has been widely studied and applied in the field of HIV prevention and treatment in recent years, and it has been proved that it can inhibit HIV-1 infection in animal models for several years.

"The breakthrough significance of the latest research is that it is further confirmed that the combination therapy of broad-spectrum neutralizing monoclonal antibody can inhibit the virus level in human body for a long time, and it shows good safety and tolerance, which is expected to become an alternative to daily ART." Professor Lu Hongzhou said.

However, combined with the latest research, Professor Lu Hongzhou said that there are still some problems to be solved urgently.

First of all, the combination therapy of monoclonal antibodies needs to screen HIV drug resistance in the infected person in advance, and the sensitivity test for monoclonal antibodies requires high test technology itself, which may limit the popularization and application of this therapy.

"HIV virus has a high frequency of mutation and a variety of immune escape strategies, and the problem of drug resistance can not be ignored. Therefore, it is also the key to develop effective extended-spectrum neutralizing antibodies and jointly identify monoclonal antibodies against different targets of the virus in the future." Professor Lu Hongzhou said.

Secondly, the study mentioned that although it is expected to greatly reduce the frequency of drug use (only twice a year), in the current course of 8 doses, once the drug is completely stopped, the virus level will eventually rebound.

"Whether the infection process can be completely changed, that is, whether the virus can be suppressed for a long time after stopping the drug, needs to be finally solved and evaluated by increasing the previous course of treatment and extending the follow-up time." The researchers said.

Professor Lu Hongzhou believes that whether "long-acting monoclonal antibody combination" can help HIV-infected people to suppress the virus in their bodies for a long time (such as several years) and achieve the final "clinical cure" by clearing the HIV virus repository still needs longer-term clinical data to support.

Source: medical profession

Editor: Song Kunlun

Proofreading: Zang Hengjia

Read the original text

Settle in 16 enterprises to create a new economic growth point in Guangyuan

Settle in 16 enterprises to create a new economic growth point in Guangyuan

—— On-the-spot report of Guangyuan JAL electromechanical high-tech industrial park project

Pavement leveling operation

Worker Yang Ziquan is carrying out board survey.

Open column language

2018 is the first year to study and implement the spirit of the 19th National Congress of the Communist Party of China, and it is also the year to deepen the city’s work style and discipline. Faye Wong, secretary of the Municipal Party Committee, pointed out at the mobilization meeting of the year to deepen the city’s work style and discipline: we should focus on large projects to promote large-scale development, carry out in-depth "big competition in projects" activities, grasp large projects, grasp large projects, and implement various cooperation such as Chengdu-Guangzhou cooperation, so as to promote a number of key projects to settle in Guangyuan at a higher level and truly form a pattern of large-scale opening and cooperation.

What should be done about the "annual competition of projects"? From now on, this newspaper will set up the column of "Annual Competition of Projects" and send reporters to the construction site to follow up on the progress of major projects in our city, so please pay attention.

Project business card

Rihang electromechanical high-tech industrial park

The proposed investment of the project is 4 billion yuan, with a total planned area of more than 800 mu and a construction area of about 700,000 ㎡. The project planning is divided into three parts: first, the layout of the factory area of small and medium-sized enterprises (production houses); Second, supporting accommodation, office buildings, canteens and medical education in the park; The third is the micro-enterprise incubation building, warehousing and logistics. The proposed construction period is 5 years, and the completion time is at the end of 2020. After the completion of the project, the annual main business income will be 4 billion yuan, the annual profit will be 500 million yuan, the annual tax revenue will be 350 million yuan, and more than 3,000 local jobs will be provided.

Image progress

Up to now, the project has invested 1.376 billion yuan, the exhibition center of Building 10-3 has been put into use, and the 10-1# and 10-2# complex buildings are being decorated and decorated on the fa? ade. It is expected to be put into use in September this year to solve the staff accommodation problem. In addition, the main body of the garden-style workshop of the project started construction of 58,000 square meters, of which 30,000 square meters of "customized workshop" is in the finishing decoration stage, and equipment installation began in June this year. In addition, 28,000 square meters of workshops of Sichuan JAL, Weilingma and other enterprises are being accelerated. It is planned to install the equipment in October this year and put it into commissioning.

Live close-up

Builders under high temperature

In the early summer, the sun is like fire, and there are crowds of people on the newly leveled ground with the fragrance of earth.

At the construction site of the mechanical and electrical high-tech industrial park in Guangyuan, the construction workers fought in the scorching sun to compete with the high temperature in order to ensure the smooth completion of the project.

There are 6 excavators, 4 road rollers, 3 loaders and more than 30 trucks. Every day, more than 300 workers are working at the scene, and the project leaders and enterprise managers are walking back and forth in the park, and the sound of the machine is rumbling and busy.

Walking into the No.8 construction plant, the sweltering heat came to my face, and the reporter soon sweated like rain, and soon the sweat soaked his eyes. The workers are so absorbed in the wall work that they can’t take care of the sweat on their foreheads.

Close to the welding site, the welder wears a helmet on his head and his face, body and feet are wrapped in thick protective clothing. It can be felt that the temperature at the welding site is much higher than that in other places. "An electric welding is about 20 kilowatts, and the staff is working in such hot weather." Ting Huang, project manager of the industrial park, told the reporter.

The reporter wanted to interview the welding workers, but two or three people were refused. Ting Huang told reporters that they are racing against time to catch up with the progress, to ensure the accuracy of each welding position, to ensure that no welding spot is missed, and to try to grab the working hours for one or two hours before noon, so that they don’t have to work at the hottest time.

Not far away, Zhang Yonggui, the young man who directed the vehicle counting, kept fanning his exercise book. The reporter stepped forward and humorously teased his dark skin. Zhang Yonggui told the reporter with a smile that he was from Mianyang. He was 27 years old and went to the construction site in November 2016. "Look at my sunburned arms and legs. I usually don’t dare to wear shorts when I go to a friend’s party. It’s too dark to see anyone." Zhang Yonggui said that the conditions on the construction site are difficult, and he must temporarily give up the nature of young people’s love for beauty and complete the task.

As for the details of the project, Ting Huang introduced that the factory building in the park adopts a frame structure, which is superior to the ordinary factory building in terms of price and 15 years longer in service life than the ordinary factory building. What’s more worth mentioning is that the garden-style decoration style is adopted in the park. For environmental protection reasons, vegetation is planted on the roof to present a new ecological industrial park.

It’s not noon yet, and the rising temperature has brought a severe test to the project construction, but every construction site still has builders who stick to their posts and concentrate on their work every day. The staff of the major engineering headquarters also share joys and sorrows with the workers, directing and supervising operations at the construction site to ensure that the project is completed on time.

Pushing measures

Accelerate the realization of the established goal of "early completion, early production and early competition for benefits"

On September 29, 2015, Zhejiang JAL Power Technology Co., Ltd. signed a tripartite investment agreement with Guangyuan Municipal People’s Government and Lizhou District People’s Government of Guangyuan City to build Guangyuan JAL Electromechanical High-tech Industrial Park, which is a provincial and municipal key investment attraction project.

As a designated project contacted by Faye Wong, secretary of the municipal party committee, Faye Wong, secretary of the municipal party committee, instructed to realize the established goal of "early completion, early production and early competition for benefits", speed up the construction progress of garden-style factory buildings in the industrial park, and show the spirit of "showing strength and seeing benefits".

According to statistics, there are 7 enterprises currently settled in the park: Weilingma Electronics Co., Ltd., Sichuan JAL Electronic Technology Co., Ltd., Sichuan Xindadi Electrical Equipment Co., Ltd., Guangyuan Tianying Precision Transmission Co., Ltd., Guangyuan Jinchuang Electronic Technology Co., Ltd., Guangyuan Yingsheng Electromechanical Equipment Co., Ltd. and Guangyuan Shuheng Electromechanical Equipment Co., Ltd. The main products are solar cell back film, electronic power and mobile phone chip, mobile phone motherboard and mobile phone assembly, auto parts and so on. In 2018, it plans to successfully attract 6 companies and is currently actively negotiating.

In order to speed up the project, the Management Committee and the Project Department hold two or three coordination meetings of key projects every month to keep abreast of the progress of key projects, sort out and analyze the crux of influencing and hindering the project progress, study the countermeasures to solve the problems, coordinate and solve the difficulties and problems encountered in the project promotion process, and ensure that the project construction is advanced as expected; At the same time, further optimize and improve the investment environment, re-investigate and re-resolve the contradictions and disputes arising in the process of enterprise construction and production, rectify and standardize the market economic order, protect the legitimate rights and interests and personal safety of investors according to law, and create a good investment and development environment for enterprises in the park.

Reporter’s notes

The pace of "strengthening" the industry is forceful.

The key to strong industry lies in industry.

According to the law and present situation of economic development, to adapt to, grasp and lead the new normal of economic development, the electromechanical industry in our city also guarantees excellent projects from supporting leading enterprises, establishing industrial groups, increasing investment attraction, establishing professional industrial zones for substation equipment production, and attaching importance to talent introduction and training.

At the same time, the city regards "strong industrial development" as the best choice, and investment promotion cadres actively move to find ways and excellent services; At the scene of each key project, the workers stepped up their construction, and the scene was full of enthusiasm … During the interview, the reporter felt the vigorous vitality and endless power of the city’s industrial development.

Standing at a new starting point, all departments at all levels in our city are further inspiring the courage to dare to compete, the atmosphere of being good at learning and the ambition to catch up, igniting the passion of catching up with learning, urging contracted projects to invest and put into production early, helping landing enterprises to innovate and benefit more, and consolidating the industrial foundation. The whole city has steadfastly and consistently grasped the unrelenting momentum of developing industries, making the pace of "strengthening industries" more forceful.

(Reporter Zhao Jingmei)

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Guangxi re-launched the project and lightly accepted 3,000 scientific and technological projects as ＂unfinished＂

　　Xinhua News Agency, Nanning, April 17th　Title: Re-taking projects and lightly accepting 3,000 scientific and technological projects as "unfinished"

　　Xinhua News Agency reporter Li Bin

　　More than 3,100 scientific and technological projects over the years have received support funds, but they have not been accepted for several years, and the funds have not been recovered according to regulations, involving more than 700 million yuan. What are the problems behind the "unfinished" science and technology projects in Guangxi?

　　More than 3,100 projects are overdue for acceptance, and some are overtime for five or six years.

　　After many whistleblowers reported for a long time that an enterprise in Liuzhou was suspected of obtaining funds for science and technology projects, the Science and Technology Department of Guangxi Zhuang Autonomous Region recently found that as of June 30, 2015, there were more than 3,100 projects that were overdue (or expired) and had not been accepted, involving 713 million yuan in funding.

　　A list of overdue scientific and technological projects obtained by the reporter shows that the projects that have not been accepted involve many natural and social sciences such as industry, agriculture, architecture, education, environmental protection and biology, and the undertaking units involve party and government organs, scientific research institutes, universities, media, enterprises, etc. Each of these projects has a completion time, and some of them have exceeded the acceptance time limit for five or six years.

　　The reporter’s investigation found that there are many hidden problems behind the "unfinished" of a large number of scientific and technological projects, which cannot be ignored.

　　Wei Zhibian, director of the Planning and Finance Department of the Science and Technology Department of the Autonomous Region, said that more than 500 of the more than 3,100 projects were before 2008. At that time, results appraisal was required, and there was no strict management method for project acceptance. It is reported that these projects will not enter the acceptance procedures and will no longer be handled publicly.

　　Liuzhou Productivity Promotion Center undertook the project of "Liuzhou Digital Science and Technology Basic Service Platform Construction" in 2011, and received 1.5 million yuan of support funds. According to the contract, it should be accepted in December 2013, but it has not applied for acceptance yet.

　　Some projects have changed, but the management department has let it go. In 2012, Guangxi Liuhua Chlor-Alkali Co., Ltd. undertook the project of producing sodium chlorate by new energy-saving technology, and the Science and Technology Department of the autonomous region gave 300,000 yuan of assistance funds, which has been overdue for more than two years and has not been accepted yet. Wang Xinrong, the project leader and deputy general manager of Liuhua Chlor-Alkali Co., Ltd., said that the project had done preliminary work at that time, and later it was terminated due to the falling price of sodium chlorate. The company later reported to the Science and Technology Department to apply for termination of the procedure, but it has not been answered.

　　According to the regulations, scientific and technological projects must be accepted four months after the expiration of the project, and it is illegal to accept them after the expiration of the time limit. More than 3,100 projects that have not been accepted on schedule have exceeded the time limit and can no longer be accepted according to regulations.

　　Some accepted projects have fraudulent acceptance. In December last year, the Science and Technology Department made a preliminary determination on a number of behaviors of Liuzhou Weite Printing Machinery Manufacturing Co., Ltd. and its affiliated enterprises to obtain scientific and technological funds: the Inspection Report in the acceptance materials of three national scientific and technological plan projects such as the company’s "CNC laminated special flexographic printing machine" and the autonomous region’s scientific and technological plan projects was forged.

　　Holding the project to find the "official hat", some projects hide the exchange of interests.

　　The reporter was informed that there were 2,588 overdue projects after 2008, and by the end of December 2015, 1,047 of them had passed the acceptance. In the second half of last year, Guangxi science and technology department concentrated on accepting overdue projects suspected of violating regulations.

　　For the overdue acceptance of the project, the financial funds invested should be recovered. According to the measures for the administration of science and technology projects issued by the Science and Technology Department of the Autonomous Region and the Department of Finance, the project fails to apply for acceptance and other situations. "The Science and Technology Department of the Autonomous Region shall record bad credit records, give a warning, informed criticism, suspend and cancel the project (project) according to the seriousness of the case, recover the allocated financial subsidy funds, and cancel the application qualification of the project (project) of the unit or relevant personnel within 1 to 3 years. Those suspected of committing a crime shall be transferred to judicial organs for handling according to law. "

　　It is understood that after sorting out a large number of projects that have not been accepted, at present, except for a few projects, the Science and Technology Department of the autonomous region has not handled the overdue projects in accordance with the regulations.

　　The survey found that among more than 3,100 overdue projects, many of the project leaders are leading cadres at or above the departmental level, and some projects were issued in 2008 but have not been accepted so far. According to a cadre of the Science and Technology Department, there are more than 100 projects in Guangxi that involve leaders at or above the deputy department level as responsible persons to undertake scientific and technological projects, and some leading cadres have taken the lead in undertaking several projects without acceptance.

　　"Some scientific research project approvers want to have a good relationship with some leading cadres, and there is an exchange of interests behind it." The cadre said that leading cadres should take the lead in undertaking the project and should abide by the regulations, but the reality is that these cadres have brought bad atmosphere.

　　When will the "only look at the materials" stop when the re-entry project is lightly accepted?

　　According to the data, from 2008 to 2014, Guangxi issued 11,222 science and technology projects (projects) in the autonomous region, and funded financial science and technology funds of 2.64 billion yuan. In addition, cities and counties still have a lot of funds to support science and technology projects.

　　"In the past, the science and technology department had some problems of rearrangement and light management. Some projects were accepted and some may not be accepted." The person in charge of Liuzhou Science and Technology Bureau said that the bureau has investigated the acceptance of science and technology projects.

　　A section chief of Liuzhou Science and Technology Bureau said: "There are too many projects. As a science and technology department, we can only look at the materials when accepting some projects." In 2015, Liuzhou Science and Technology Bureau spent 300,000 yuan to entrust a third-party organization to conduct external audit of the projects implemented since 2010, but it can only cover about 30% of the projects.

　　Chen Shengwen, director of the Policy and Regulation Supervision Department of the Science and Technology Department of the Autonomous Region, said that the Science and Technology Department is taking measures to strengthen supervision over the problems existing in the fund management of science and technology projects. Set up a special working group, arrange special funds, organize and entrust professional institutions to conduct major investigations and clean-ups on key and major scientific and technological projects implemented in the past three years to plug loopholes; Revise the management measures for the acceptance of Guangxi science and technology projects, and innovate the supervision methods of science and technology projects during and after the event.

　　The reporter’s investigation found that science and technology funds play a positive role in promoting scientific and technological innovation, but there are also some problems in the process of project establishment, such as "looking for relationships to fight for projects", "looking for things after having money" and "continuing to spend money without money".

　　Chen Bulei, a professor at Southwest University of Political Science and Law, suggested improving the systematic and targeted use of science and technology funds. Projects that cannot be accepted and closed should recover funds in time and be dealt with according to regulations; Science and technology projects should establish a public publicity system, introduce social supervision, and disclose the project name, undertaker, project leader, amount, time limit, completion and other information from the beginning of the project. If the project is not completed, it shall be liable for breach of contract or violation of law.

Shenyang： Being a director is not that serious and will not be affected by doubt.

Special feature of 1905 film network"People’s life is actually short, and sometimes it’s the same as sleeping: when your eyes are closed and opened, a day passes; As soon as you close your eyes and don’t open them, this life will pass. "

This quite classic line comes from the sketch "Not Bad Money" of CCTV Spring Festival Gala in 2009. Just a few minutes’ performance on the stage made hundreds of millions of TV viewers remember Xiao Shen Yang, even his "English name" Xiao Shen Yang, on the night of that year.

After that, in addition to sketch creation, Xiao Shenyang began to participate in the filming of big-screen works as a film actor, and he participated in the works directed by Zhang Yimou, Wong Kar-wai and the regular series of Spring Festival stalls every year. In the upcoming comedy, he finally completed a "cross-border" again and became a film director.

The day before the interview, Xiao Shenyang just finished a road show in more than 20 cities. Although it is hard to hide his fatigue, it still makes him feel very rewarding to be in close contact with the audience in a new identity: "Everyone started to know me through (the stage) in 2009, and this roadshow made (everyone) know more about me."

The explosion of red nine years ago not only made little Shenyang gain attention and opportunities, but also brought prejudice, doubt and even abuse. "Maybe it’s mainly because of my background, and I don’t have a deep culture. People may look down on me when farmers come to be directors." Today, during the publicity of the film debut "The Fierce Worm Crossing the River", Xiao Shenyang still feels helpless about some external comments and opinions.

"Everyone has made this topic too serious. For me, it is actually to learn a trade to enrich myself. When an actor learns to be a director, it will help him see things that he could not see when he was an actor before. " Xiao Shenyang admits that his original intention of filming "The Fierce Worm Crossing the River" is actually very simple. "Everyone (now) says this matter is particularly serious, saying that the threshold (as a director) is low, and when a bad film is filmed, and so on. I think nothing is wrong. If I want to do one thing well, no one can stop me from studying. "

"If you have time to swear, you can also study hard by yourself." Xiao Shenyang gave such a "counterattack" gently.

"Being a director is not that serious. I hope the new director will have less negative energy."

During the interview, Xiao Shenyang mentioned this time point in 2009 many times. There is no doubt that the performance on the stage of the Spring Festival Evening is both a turning point and a new "beginning" for his career.

"So what do you want to share about yourself in 2009?"

"Maybe everyone knew me through that night, and it was hard for everyone to see my previous years." Xiao Shenyang said.

In 1995, at the age of 14, Xiao Shenyang began to study duet in the Art Troupe. From Tieling to Jilin and then to Shenyang, in those days, he performed in the theater every day. "It is not easy for people of all kinds to support their families in order to earn two dollars (work here) every day." In 2006, he gradually began to get the opportunity to appear in TV programs, and finally boarded the stage of the 2009 Spring Festival Gala.

The "Tieling Waiter" wearing a Scottish plaid skirt became an instant hit. Little Shenyang gained more attention and opportunities, and began to participate in the big screen works as a film and television actor. In that year, Xiao Shenyang filmed Zhang Yimou’s work "Surprise with Three Guns", and in 2013, he made a guest appearance in Wong Kar-wai’s martial arts film "The Master", and became a member of the The Journey to the West series, a frequent visitor in the Spring Festival.

This time as a cross-border director, Xiao Shenyang’s initial idea was actually very simple. "I don’t really have a desire (to be a director), that is, friends chat together and say that they want to do such a thing. Actually, I am against it, because I care about what people think of me. Many people may know a little about me and don’t know what I am like behind in 2009, so I am afraid that some people will talk about it. "

After figuring it out, Xiao Shenyang wanted to do it to the end: "It seems difficult, but it’s nothing. Everyone has taken this topic too seriously. (For me) it’s just learning a trade to enrich myself, nothing special. When an actor learns to be a director, it will help him see things that he could not see when he was an actor before. "

After the exposure of the project "Fierce Insects Crossing the River", while gaining support, Little Shenyang was once again attacked by netizens and fans — — Small Shenyang as a director? Some people’s first reaction is "the director’s threshold is too low" and "the film will definitely be ruined again" … … "It may be mainly because of my background and lack of deep culture. People may look down on me when farmers come to be directors, so there will be such a voice."

Faced with these "messy" remarks, Xiao Shenyang chose to use self-deprecating methods to resolve them. "In fact, I have more doubts about myself than anyone else," he replied in a preview special full of questioning barrage. "I just told these people. China movies are very good now, and we are making progress, and there is too much room for improvement. I want to call on these people to support China movies, support new directors like me, give some strength, and don’t always give some negative energy. "

"Making a movie depends on the flow of actors, and it will not be affected by box office and doubts."

Although it is the first time to direct a film, Xiao Shenyang’s "Fierce Worm Crossing the River" invited a group of familiar faces to join. He admitted that he was very lucky. Many actors and seniors agreed to take part in the show just in time. For example, Jin Shijie, who was recuperating in Taiwan Province at that time, said, "Mr. Jin is over 70, and it will take four or five hours to shoot a film on the spot, so people just sit there silently without saying’ Shoot me quickly’. I was embarrassed to say hello to the teacher and said,’ Mr. Jin will have to wait for a while’, and the teacher said,’ It’s okay, you shoot yours, don’t worry about me’. They are very supportive of me and have never given me any pressure. "

It is naturally best for the new director’s works to be blessed by some traffic stars with hot topics. However, Xiao Shenyang admits that there is nothing in his movie: "I think it is useless to invite. If the script really needs it, won’t it be counterproductive if there is no such character in the script?"

"I like the words of director Jason Wu very much. It’s not expensive to use the right one." Xiao Shenyang said, "It’s not necessarily a good film to pile up a movie with stars. Besides, it’s out of date. Now the audience is very smart. No one watches the stars mainly because they read stories."

So what story does Xiao Shenyang’s "The Fierce Worm Crossing the River" tell? According to him, his "nobody at the bottom of Northeast China" will go to Taiwan Province, a treasure island, and experience a series of embarrassing events there. Whether the sparks between the two contrasting dialects "Dongbei Dialect" and "Taiwan Dialect" are wonderful or not, Xiao Shenyang is also looking forward to the feedback from the audience.

The aesthetic differences between the North and the South have always made many comedians feel afraid in their creation, but Shenyang, which has rich performance experience, is not nervous about this: "We used to tour (in the South) and it was hard to get a ticket. At the scene, we directly responded to the burden audience, so there was not much worry. This is especially true for movies. It is a story. If the story develops, it will naturally make you laugh. " At the same time, in order to avoid the "sketch fragment wind" of comedians making movies, Xiao Shenyang also specially invited the producer who had been in charge of and waited for films to check for himself. "Don’t worry, the film is full!"

On June 15th, "Crossing the River" will land in the cinema. The summer file is approaching, and the competition in the mainland film market is becoming more and more fierce. There is a Hollywood giant painting with the debut of Xiao Shenyang. This is undoubtedly a great pressure for a new director. However, Xiao Shenyang firmly stated that no matter how the film finally performed, it would not affect his future direction.

"This is my first work, and it still has room for growth. I will be very concerned about everyone’s comments. I am very, very receptive to the opinions or criticisms given to me by the audience after watching the film, and even I need to swear. There are many shortcomings in the first work. "Xiao Shenyang sincerely expressed his willingness to listen to the opinions of the audience and continue to work hard and make progress. "So I don’t care whether the box office is good or not. I finished it with my heart, that is, I gave it to the audience to judge. Whether the box office is good or not, I have just begun."

Xiao Shenyang revealed that he actually likes Hollywood’s "heavy industry" movies very much. For example, the one released before is one of his favorites. However, as for his future direction, he revealed that "let everyone laugh first": "We comedians are really the happiest thing to see the audience’s laughter at that moment on stage. So I’d better shoot some movies that will make everyone happy first. If everyone is tired of watching it, I will shoot another one. "

Sha Zukang： China has become the engine driving world economic growth.

　　　　Xinhuanet United Nations, November 24th Interview: China Becomes the Engine of World Economic Growth ―― Interview with UN Under-Secretary-General Sha Zukang.

　　　　Xinhua News Agency reporter Wang Xiangjiang Wu Zhiqiang

　　　　This year marks the 30th anniversary of China’s reform and opening up. From a diplomat to the UN Under-Secretary-General for Economic and Social Affairs, Sha Zukang has witnessed the great changes in China. In an exclusive interview with Xinhua News Agency recently, he said that after 30 years of reform and opening up, China has become one of the engines driving world economic growth.

　　　　Sha Zukang pointed out that China has achieved sustained and high-speed development in the past 30 years of reform and opening up, with its economic aggregate increasing by about 15 times and its foreign trade volume increasing by more than 100 times. In the history of modern world development, the sustained and rapid development of China is rare.

　　　　Sha Zukang said that China’s contribution to reducing the world’s poor population is also obvious to all. Over the past 30 years, about 500 million people in China have escaped from absolute poverty, exceeding and ahead of schedule the goal of halving the poverty population in 2015 set by the United Nations Millennium Development Goals.

　　　　Sha Zukang talked about the reasons for the success of China’s reform and opening up from the perspective of economic development. First of all, the goal of China’s reform and opening up is clear, that is, to promote economic and social development by liberating productive forces; Second, formulate various reform and opening-up measures realistically. China’s reform and opening-up emphasizes China’s characteristics and national conditions, which not only boldly breaks through the traditional "planned economy" frame, but also does not blindly copy the western capitalist model; Third, the process of reform and opening-up should be promoted step by step. China’s reform and opening-up measures, starting from the "responsibility system" in rural areas, to the reform of prices, foreign trade system, state-owned enterprises, and then to the financial system, have been carried out step by step and steadily, without adopting the so-called "shock therapy".

　　　　Sha Zukang said that another main reason for the success of China’s reform and opening up is to base itself on the national conditions. The development of a country mainly depends on its own efforts. The development experience of foreign countries can be used for reference, but it is not suitable for copying and "grafting", and it needs to be studied and explored in light of its own national conditions.

　　　　Sha Zukang pointed out that China does not want other countries to impose its model on China, and China has always stressed that different countries can have different models of economic development, which is also an important reason for China’s success. He said that China accounts for one fifth of the world’s population, and the areas involved in the process of reform, opening up and development are unprecedented. China has encountered many difficulties and problems in the process of reform and opening up, and China has also accumulated many experiences and lessons in dealing with and solving these difficulties and problems, some of which can be used for reference by other developing countries.

　　　　When talking about China’s cooperation with other developing countries, Sha Zukang said that China has always attached great importance to it and actively promoted cooperation with other developing countries, that is, "South-South" cooperation. When negotiating various world development issues at the United Nations and other occasions, China always stands in the position of safeguarding the interests of developing countries.

　　　　When talking about the relationship between China’s reform and opening up and the development of the United Nations, Sha Zukang said that development is one of the three pillars of the work of the United Nations and the foundation of the other two pillars-peace, security and human rights. China’s achievements in reform and opening up in the past 30 years are consistent with the purpose of the United Nations to promote common development in the world.

　　　　He said that China is the largest developing country and the fastest growing economy, and the United Nations is the most extensive, representative and authoritative intergovernmental international organization in the world. With the deepening of economic globalization, the development of China is increasingly inseparable from the world, and the world needs China more. The cooperation between the United Nations and China in the field of development has a profound foundation and broad prospects.

　　　　Sha Zukang also pointed out that China is still a developing country with low and middle income and is facing many challenges, such as the income gap between the rich and the poor and environmental problems. But these are developing problems that can be solved through in-depth reform and opening up. In fact, in recent years, the China government has put forward the development program of "people-oriented" and "harmonious society" and the Scientific Outlook on Development, emphasizing the quality of development rather than simply pursuing the growth rate of GDP, which has laid a policy foundation for solving new problems in development and ensuring the sustainable development of China’s economy.

　　　　Sha Zukang said: "A government that has clear development goals and is committed to achieving these goals, an economic system that can stimulate productivity and mobilize enthusiasm, and the hard work of the people are the basic experiences of China’s successful development."

The World Bank predicts that China’s economy will grow by 7.5% next year.

　　　　China Daily Online News: In its latest quarterly report, the World Bank affirmed the recent measures taken by the China government to stimulate the economy, and predicted that China’s economy will grow by 7.5% next year. < < < detailed

The International Monetary Fund predicts that the economies of Asian countries will slow down sharply.

　　　　Zhongxin. com, November 25th, International CurrencyfundIn the Asia-Pacific Economic Outlook report published on the 24th, the organization said that the world financial crisis will last until the end of 2009. Against this background, Asia’s growth may slow sharply and its vulnerability will increase.

　　　　According to the UN website, the international currencyfundThe organization’s Asia-Pacific Economic Outlook report points out that before the end of 2009, Asia’s economic growth will slow down significantly. As the global economic slowdown has affected exports, it is expected that the growth in Asia will be mainly driven by domestic demand. However, it remains to be seen whether domestic demand can stand the test under the situation of sharp decline in export growth and more severe financial conditions. < < < detailed

Changjiang Daily: During the period of economic adjustment, it is especially necessary to stabilize social sentiment.

　　　　Xinhua News Agency’s International Herald Tribune reported that since 2008, many mass incidents have shaken China. The article also takes "contending with the people is the culprit" as the subtitle, trying to explore the deep-seated reasons behind mass incidents and sort out the rational ways to deal with incidents, resolve contradictions and Fushun emotions.

　　　　Experience at home and abroad tells us that economic problems and social problems must be intertwined and influenced each other. At present, the deeply spreading international financial crisis has swept the world, which also affects the sensitive nerves of China’s economy. In October, this year’s fiscal revenue showed negative growth in a single month for the first time. The combination of background factors, such as the closure of enterprises caused by the economic downturn and the cold employment, and the interest differentiation brought about by the social transition in China, makes it possible to highlight and sharpen all kinds of social contradictions, and the resulting social and psychological frustration and unstable factors will inevitably not exist alone in individual industries and groups. In such a relatively special period, effectively resolving social contradictions and stabilizing social sentiment will be a realistic task that the government must face in addition to expanding domestic demand and boosting the economy. < < < detailed